Rolf G Boot Selected Research

Aziridines (Ethyleneimines)

5/2016

Detection of Active Mammalian GH31 α-Glucosidases in Health and Disease Using In-Class, Broad-Spectrum Activity-Based Probes.

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Rolf G Boot Research Topics

Disease

33	Gaucher Disease (Gaucher's Disease) 01/2022 - 07/2002
9	Fabry Disease (Fabry's Disease) 12/2021 - 02/2008
5	Inflammation (Inflammations) 01/2022 - 10/2005
5	Asthma (Bronchial Asthma) 01/2016 - 10/2005
5	Insulin Resistance 01/2011 - 09/2008
4	Type 2 Diabetes Mellitus (MODY) 07/2011 - 01/2009
3	Disease Progression 01/2016 - 04/2008
2	Parkinson Disease (Parkinson's Disease) 01/2022 - 01/2019
2	Neoplasms (Cancer) 01/2020 - 05/2012
2	Lysosomal Storage Diseases (Lysosomal Storage Disease) 01/2020 - 02/2008
2	Globoid Cell Leukodystrophy (Krabbe Disease) 01/2020 - 01/2017
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2018 - 01/2015
2	Type C Niemann-Pick Disease (Niemann Pick Disease, Type C) 03/2016 - 04/2006
2	Multiple Sclerosis 04/2010 - 02/2006
2	Sarcoidosis (Schaumann Disease) 01/2010 - 10/2003
2	Body Weight (Weight, Body) 11/2009 - 02/2009
2	Hepatocellular Carcinoma (Hepatoma) 02/2009 - 09/2008
1	Neuroinflammatory Diseases 01/2022
1	Mannosidase Deficiency Diseases (Mannosidosis) 01/2020
1	GM2 Gangliosidoses (GM2 Gangliosidosis) 01/2020
1	Metachromatic Leukodystrophy (Sulfatide Lipidosis) 01/2020
1	Nervous System Diseases (Neurological Disorders) 01/2017
1	Glycogen Storage Disease Type II (Pompe's Disease) 05/2016
1	Airway Obstruction (Choking) 01/2016
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2016
1	Melanoma (Melanoma, Malignant) 01/2016
1	Fucosidosis 05/2015
1	Farber Lipogranulomatosis 04/2015
1	Cerebellar Ataxia (Dysmetria) 01/2015
1	Motor Disorders 01/2015
1	Synucleinopathies 01/2015
1	Ataxia (Dyssynergia) 01/2015
1	Airway Remodeling 08/2013
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2011
1	Atherosclerosis 04/2010
1	Hyperglycemia 01/2010
1	Sphingolipidoses (Sphingolipidosis) 01/2009
1	Pathologic Processes 01/2009
1	Renal Insufficiency (Renal Failure) 02/2008
1	Multiple Myeloma 07/2007

Drug/Important Bio-Agent (IBA)

19	Glucosylceramidase (Glucocerebrosidase)IBA 01/2022 - 01/2004
13	Glucosylceramides (Glucocerebrosides)IBA 01/2022 - 01/2004
12	EnzymesIBA 01/2017 - 07/2002
10	Biomarkers (Surrogate Marker)IBA 01/2016 - 01/2004
9	chitotriosidaseIBA 01/2016 - 07/2002
7	GlycosphingolipidsIBA 01/2020 - 09/2004
6	sphingosyl beta-glucosideIBA 01/2022 - 10/2011
6	ChitinasesIBA 01/2016 - 10/2005
6	LipidsIBA 04/2010 - 10/2003
5	GlucosidasesIBA 01/2021 - 01/2011
5	ceramide glucosyltransferaseIBA 03/2016 - 09/2008
4	GalactosidasesIBA 12/2021 - 08/2014
3	alpha-Galactosidase (Beano)IBA 01/2017 - 02/2008
3	Proteins (Proteins, Gene)FDA Link 08/2013 - 01/2010
3	N- (5- adamantane- 1- yl- methoxy- pentyl)deoxynojirimycinIBA 11/2009 - 09/2008
2	Acid CeramidaseIBA 01/2022 - 04/2015
2	Lysergic Acid Diethylamide (LSD)IBA 12/2021 - 04/2008
2	globotriaosylceramide (globotriosylceramide)IBA 12/2021 - 02/2008
2	cyclophellitolIBA 01/2019 - 05/2016
2	Pharmaceutical PreparationsIBA 01/2017 - 07/2011
2	CholesterolIBA 03/2016 - 02/2009
2	Glycoside Hydrolases (Endoglycosidases)IBA 05/2014 - 11/2012
2	Insulin (Novolin)FDA Link 11/2009 - 02/2009
1	globotriaosyl lysosphingolipidIBA 12/2021
1	Polysaccharides (Glycans)IBA 01/2020
1	mannosyl-oligosaccharide 1,3 - 1,6-alpha-mannosidaseIBA 01/2020
1	conduritol epoxideIBA 01/2019
1	EndocannabinoidsIBA 01/2018
1	Galactosylceramides (Galactocerebrosides)IBA 01/2017
1	Psychosine (Galactosylsphingosine)IBA 01/2017
1	GalactosylceramidaseIBA 01/2017
1	GlycogenIBA 05/2016
1	Aziridines (Ethyleneimines)IBA 05/2016
1	4-nitrophenyl-alpha-glucosidaseIBA 05/2016
1	AcidsIBA 05/2016
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2016
1	AllergensIBA 01/2016
1	ProteomeIBA 01/2016
1	Glycoproteins (Glycoprotein)IBA 01/2016
1	IgA receptor (protein B)IBA 01/2016
1	alpha-L-Fucosidase (Fucosidase)IBA 05/2015
1	SphingosineIBA 04/2015
1	Protein Isoforms (Isoforms)IBA 04/2015
1	Hexosaminidases (Hexosaminidase)IBA 11/2014
1	Fluorescent Dyes (Fluorescent Probes)IBA 11/2014
1	HydrolasesIBA 08/2014
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 08/2013
1	Mannose ReceptorIBA 10/2011
1	1-Deoxynojirimycin (1 Deoxynojirimycin)IBA 01/2010
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 01/2010
1	ChitinIBA 07/2009
1	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 02/2009
1	Triglycerides (Triacylglycerol)IBA 02/2009
1	SterolsIBA 02/2009
1	SphingolipidsIBA 01/2009
1	Chemokine CCL4IBA 07/2007

Therapy/Procedure

5	Therapeutics 01/2020 - 04/2006
4	Enzyme Replacement Therapy 08/2009 - 10/2003
1	Lasers (Laser) 01/2016
1	Enzyme Therapy 05/2014